Profile

ANDREAS MENTIS

BIOPATHOLOGIST (MICROBIOLOGIST)

DIRECTOR, CENTRAL LABS, IASO Medical Services Lab Sector Coordinator
  1. General
  2. Maternity - Gynecology
  3. Pediatric
  • Education & Academic Titles
    • 1979: MD, Medical School, University of Athens
    • 1986: Specialty in Biopathology (Laboratory Medicine)
    • 1988: Training in Sexually Transmitted Diseases, Hopital Saint-Louis, Paris
    • 1997: Subspecialty in Clinical Microbiology
  • PhD Thesis

    1983: PhD in Public Health, Medical School, University of Athens

  • Professional Experience
    • 1987 – 2020: Researcher, Hellenic Pasteur Institute, Laboratory of Medical Microbiology
    • Since 2005: Researcher Grade A’, Hellenic Pasteur Institute, Head of Public Health Laboratories (PHL), which include the following laboratories:
      • Diagnostic Services Laboratory for Infectious and Neurodegenerative Diseases
      • National Influenza Reference Laboratory for Southern Greece (WHO recognized)
      • National Measles/Rubella Reference Laboratory (WHO recognized) and
      • National Polio/Enterovirus Reference Laboratory (WHO recognized)

    In 2020 the Public Health Laboratories were appointed by the Ministry of Health as National Reference Laboratory for COVID-19

  • Clinical Interest

    Helicobacter pylori infection, congenital infections, viral respiratory infections, COVID-19 infection

  • Awards & Distinctions
    • Award of the Athens Academy of Science in 1996 to Dr Mentis for his contribution to Clinical Microbiology in Greece, for the period 1991-1995
    • The 2020 special prize of the Hellenic Institute of Customer Service was awarded to the Diagnostic Services Laboratory and the Public Health Laboratories of the HPI for their contribution against the COVID-19 pandemic
  • Recent Publications

    Year 2021

    • Fotis C, Meimetis N, Tsolakos N, et al. Accurate SARS-CoV-2 seroprevalence surveys require robust multi-antigen assays, accepted for publication in Scientific Reports
    • Papadakis G, Pantazis A, Fikas N, et al. Real-time colorimetric LAMP methodology for quantitative nucleic acids detection at the point-of-care. Submitted, 2021
    • Maltezou HC, Vorou R, Papadima K, et al. Transmission dynamics of SARS-CoV-2 within families with children in Greece: a study of 23 clusters. J Med Virol. 2021 Mar;93(3):1414-1420. doi: 10.1002/jmv.26394
    • Maltezou HC, Raftopoulos V, Vorou R, et al. Association between upper respiratory tract viral load, comorbidities, disease severity and outcome of patients with SARS-CoV-2 infection. J Infect Dis. 2021 Jan 3:jiaa804. doi: 10.1093/infdis/jiaa804. Online ahead of print.PMID: 33388780
    • Galani IE, Rovina N, Lampropoulou V, et al. Untuned antiviral immunity in COVID-19 revealed by temporal type I/III interferon patterns and flu comparison. Nat Immunol. 2021 Jan;22(1):32-40. doi: 10.1038/s41590-020-00840-x. PMID: 3327763
    • Politis C, Papadaki M, Politi L, et al. Post-donation information and haemovigilance reporting for COVID-19 in Greece: Information supporting the absence of SARS-CoV-2 possible transmission through blood components. Transfus Clin Biol. 2021,28:55-59. doi: 10.1016/j.tracli.2020.10.007. PMID: 33096208

    Year 2020

    • Terpos E, Mentis A, Dimopoulos M. Loss of Anti–SARS-CoV-2 Antibodies in Mild Covid-19. October 22, 2020. N Engl J Med 2020; 383:1694-1698. DOI: 10.1056/NEJMc2027051
    • Liontos M, Kaparelou M, Karofylakis E, et al. Chemotherapy resumption in ovarian cancer patient diagnosed with COVID-19. Gynecol Oncol Rep. 2020 Jul 30;33:100615. doi: 10.1016/j.gore.2020.100615.PMID: 32766415
    • Maltezou HC, Magaziotou I, Dedoukou X, et al. Children and Adolescents With SARS-CoV-2 Infection: Epidemiology, Clinical Course and Viral Loads. Pediatr Infect Dis J. 2020 Dec;39(12):e388-e392. doi: 10.1097/INF.0000000000002899, PMID: 33031141
    • Mogling R, Meijer A, Berginc N, et al. Delayed Laboratory Response to COVID-19 Caused by Molecular Diagnostic Contamination. Emerg Infect Dis. 2020 Aug;26(8):1944-1946. doi: 10.3201/eid2608.201843. PMID: 32433015
    • Pogka V, Emmanouil M, Labropoulou S, et al. Molecular characterization of enteroviruses among hospitalized patients in Greece, 2013-2015. J Clin Virol. 2020 Jun;127:104349. doi: 0.1016/j.jcv.2020.104349. PMID: 32339946.
    • Maltezou HC, Asimakopoulos G, Stavrou S, et al. Effectiveness of quadrivalent influenza vaccine in pregnant women and infants, 2018-2019. Vaccine. 2020 Jun 15;38(29):4625-4631. doi: 10.1016/j.vaccine.2020.04.060. Epub 2020 May 8.PMID: 32402751
    • Emmanouil M, Evangelidou M, Papa A, Mentis A. Importation of dengue, Zika and chikungunya infections in Europe: the current situation in Greece. New Microbes New Infect. 2020 Mar 18;35:100663. doi: 10.1016/j.nmni.2020.100663. eCollection 2020 May.PMID: 32300479
    •  Alm E, Broberg EK, Connor T, et al. Geographical and temporal distribution of SARS-CoV-2 clades in the WHO European Region, January to June 2020. Euro Surveill. 2020 Aug;25(32):2001410. doi: 10.2807/1560-7917.ES.2020.25.32.2001410
    • Melidou A, Pereyaslov D, Hungnes O, et al. Virological surveillance of influenza viruses in the WHO European Region in 2019/20 - impact of the COVID-19 pandemic. Euro Surveill. 2020 Nov;25(46):2001822. doi: 10.2807/1560-7917.ES.2020.25.46.2001822. PMID: 33213683
    • Terpos E, Politou M, Sergentanis T, etal.  Anti-SARS-CoV-2 Antibody Responses in Convalescent Plasma Donors Are Increased in Hospitalized Patients; Subanalyses of a Phase 2 Clinical Study. Microorganisms. 2020 Nov 28;8(12):1885. doi: 10.3390/microorganisms8121885
    • Mouratidou E, Lambrou A, Andreopoulou A, et al. Influenza vaccine effectiveness against hospitalization with laboratory-confirmed influenza in Greece: A pooled analysis across six seasons, 2013-2014 to 2018-2019. Vaccine. 2020 Mar 10;38(12):2715-2724. doi: 10.1016/j.vaccine.2020.01.083. PMID: 32033848
    • Mook P, Meerhoff T, Olsen SJ, et al; Collective of the WHO European Region, European Influenza Surveillance Network . Alternating patterns of seasonal influenza activity in the WHO European Region following the 2009 pandemic, 2010-2018. Influenza Other Respir Viruses. 2020 Mar;14(2):150-161. doi: 10.1111/irv.12703. Epub 2020 Jan 16. PMID: 31944604
    • Georgopoulos SD, Michopoulos S, Rokkas T, et al. Hellenic consensus on Helicobacter pylori infection. Ann Gastroenterol. 2020 Mar-Apr;33(2):105-124. doi: 10.20524/aog.2020.0446.PMID: 32127732
    • Syridou G, Drikos I, Kapetanakis M, et al. Human Herpesvirus 7-Related Acute Encephalopathy with Biphasic Seizures and Late Reduced Diffusion. Pediatr Infect Dis J. 2020 Feb;39(2):170-172. doi: 10.1097/INF.0000000000002557. PMID: 3192943
    • Maltezou HC, Kossyvakis A, Lytras T, et al. Circulation of Influenza Type B Lineages in Greece During 2005-2015 and Estimation of Their Impact. Viral Immunol. 2020 Mar;33(2):94-98. doi: 10.1089/vim.2019.0110. PMID: 31905328
    • Melidou A, Hungnes O, Pereyaslov D, et al. Predominance of influenza virus A(H3N2) 3C.2a1b and A(H1N1)pdm09 6B.1A5A genetic subclades in the WHO European Region, 2018-2019. Vaccine. 2020 Jul 31;38(35):5707-5717. doi: 10.1016/j.vaccine.2020.06.031. Epub 2020 Jul 3. PMID: 32624252
    • Karageorgou I, Kogerakis N, Labropoulou S, et al. Q Fever Endocarditis and a New Genotype of Coxiella burnetii, Greece. Emerg Infect Dis. 2020 Oct;26(10):2527-2529. doi: 10.3201/eid2610.191616.PMID: 32946732
    • Vlachogianni G, Hassapopoulou-Matamis H, Politis C, et al. A case of COVID-19 Convalescent Plasma Donation in Greece: Directed donation for compassionate use in the donor’s critically ill father. Transfus Clin Biol. 2020 Nov;27(4):269-270. doi: 10.1016/j.tracli.2020.09.001. Epub 2020 Sep 25.PMID: 33071174
    • Pervanidou D, Vakali A, Georgakopoulou T, et al. West Nile virus in humans, Greece, 2018: the largest seasonal number of cases, 9 years after its emergence in the country. Euro Surveill. 2020 Aug;25(32):1900543. doi: 10.2807/1560-7917.ES.2020.25.32.1900543. PMID: 32794446
    • Van Walle I, Leitmeyer K, Broberg K. et al. Meta-analysis of the clinical performance of commercial SARS-CoV-2 nucleic acid, antigen and antibody tests up to 22 August 2020. MeRxiv (preprint) doi: https://doi.org/10.1101/2020.09.16.20195917
  • Membership in Societies and Editorial Boards
    • Editorial Board of national and international journals in the field of Medical/Clinical Microbiology.
    • Organizing/Scientific committees of national and international congresses on Helicobacter pylori.
    • Since 1993: American Society for Microbiology
    • Since February 2020: Greek National COVID-19 Expert Committee
    • Up to 2020 Dr Andreas Mentis was ECDC’s Microbiology focal point for influenza in Greece
  • Research

    Participation in several national and European research projects. Research interests include: Helicobacter pylori antibiotic resistance and pathogenesis, molecular epidemiology of respiratory viruses and enteroviruses, antiviral resistance, development and evaluation of diagnostic laboratory tests, probiotics, microbiome, and host-response in infections